Posted on 16th Jun 2018 15:05:34 in GATE Biotechnology
This post is for the aspirants of GATE-BT-2019
As per the latest trend for GATE-BT
Total No of questions: 65 Total Number of marks: 100
General aptitude: 10 questions; 15 marks Biotech: 55 questions; 85 marks
Negative marking for 1 mark questions: 1/3 Negative marking for 2 mark questions: 2/3
In the 2018 GATE-BT PAPER
Percentage of questions devoted to Genetics: 6%
Total weightage of marks: 8%
Prescribed syllabus for genetics
Mendelian inheritance; Gene interaction; Complementation; Linkage, recombination and chromosome mapping; Extrachromsomal inheritance; Chromosomal variation; Population genetics; Transposable elements, Molecular basis of genetic diseases and applications.
Also included here: Microbial genetics: Plasmids, transformation, conjugation, transduction
For GATE aspirants, the questions are primarily numerical based. Therefore prior practice in problem solving is crucial. The only requirement is the clarity of basic concepts.
Following is the topic-wise analysis of the paper.
Mendelian inheritance: Basic concepts and laws of Mendelian inheritance. Analysis of inheritance patterns (autosomal dominant, autosomal recessive, sex-linked etc; inheritance of X and Y chromosomes and their genes.). Predicting the results of various types of crosses. Most calculations are probability based. At least one question based on this.
Gene interaction: Problems based on the genetic dissection of biochemical pathways by mutant supplementation
Extrachromsomal inheritance: Distinguishing between Mendelian and non-mendelian inheritance. Concepts of cytoplasmic inheritance, CMS, maternal inheritance, infectious heredity and maternal effects.
Chromosomal variation: Structural and Numerical aberrations of chromosomes; At least one question based on the concepts of euploidy and polypoidy etc.
Population genetics: Hardy Weinberg law. Calculating gene and genotype frequencies. Factors affecting gene frequencies in a population. At least one question based on this topic , most commonly about gene and genotype frequency.
Linkage, recombination and chromosome mapping: Concept of linkage. Departure from Mendelian ratios, in the inheritance pattern of linked genes. Calculation of recombination frequencies between linked genes. Linkage mapping by determining the distance between genes, and their relative order on the chromosome. Concept of synteny.
Microbial genetics: Basic concepts of conjugation, transduction and transformation, mutagenicity testing in bacteria
